Chronic kidney disease symptoms often develop slowly and may not be noticeable in the early stages. Common symptoms include persistent fatigue, weakness, swelling in the feet, ankles, or face due to fluid retention, and changes in urination such as increased frequency at night or reduced urine output. People with chronic kidney disease may also experience nausea, loss of appetite, muscle cramps, dry and itchy skin, and difficulty concentrating. As the condition progresses, high blood pressure, shortness of breath, and anemia can occur. Early recognition of chronic kidney disease symptoms is important, as timely diagnosis and proper treatment can help slow disease progression and improve quality of life.